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Can mRNA containing synthetic n1-methylpseudouridine nucleosides be reverse transcribed into DNA? If so, then will the n1-methylpseudouridine be able to pair up with DNA nucleotides other than Adenine, assuming that it can pair up with Adenine? And is there any potential for wobble base pairing?

by /u/mr-logician in /r/askscience

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