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Aside from people with celiac disease/wheat allergies, is their any meaningful way that eating wheat affects the body that other grains/carbs do not?

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Aside from people with celiac disease/wheat allergies, is their any meaningful way that eating wheat affects the body that other grains/carbs do not?	1
Does the body use up more energy digesting food that is swallowed whole as opposed to food that is chewed and broken up first?	1