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Does the body expend/use-up non-macronutrient ingestibles (e.g., medicines/stimulants/vitamins) in order to extract their benefits?

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Does the body expend/use-up non-macronutrient ingestibles (e.g., medicines/stimulants/vitamins) in order to extract their benefits?	1
If we could make an artificial brain cells, could we transfer consciousness?	1